Lippincott Illustrated Reviews: Biochemistry 7th Edition
Proteins are the most abundant and functionally diverse molecules in living systems. Virtually every life process depends on this class of macromolecules. For example, enzymes and polypeptide hormones direct and regulate metabolism in the body, whereas contractile proteins in muscle permit movement. In bone, the protein collagen forms a framework for the deposition of calcium phosphate crystals, acting like the steel cables in reinforced concrete. In the bloodstream, proteins, such as hemoglobin and albumin, transport molecules essential to life, whereas immunoglobulins fight infectious bacteria and viruses. In short, proteins display an incredible diversity of functions, yet all share the common structural feature of being linear polymers of amino acids. This chapter describes the properties of amino acids. Chapter 2 explores how these simple building blocks are joined to form proteins that have unique three-dimensional structures, making them capable of performing specific biologic functions.
UNIT I: Protein Structure and Function Chapter 1:Amino Acids Chapter 2:Protein Structure Chapter 3:Globular Proteins Chapter 4:Fibrous Proteins Chapter 5:Enzymes
UNIT II: Bioenergetics and Carbohydrate Metabolism Chapter 6:Bioenergetics and Oxidative Phosphorylation Chapter 7:Introduction to Carbohydrates Chapter 8:Introduction to Metabolism and Glycolysis Chapter 9:Tricarboxylic Acid Cycle and Pyruvate Dehydrogenase Complex Chapter 10:Gluconeogenesis Chapter 11:Glycogen Metabolism Chapter 12:Monosaccharide and Disaccharide Metabolism Chapter 13:Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate Chapter 14:Glycosaminoglycans, Proteoglycans, and Glycoproteins
UNIT III: Lipid Metabolism Chapter 15:Dietary Lipid Metabolism Chapter 16:Fatty Acid, Triacylglycerol, and Ketone Body Metabolism Chapter 17:Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism Chapter 18:Cholesterol, Lipoprotein, and Steroid Metabolism
UNIT IV: Nitrogen Metabolism Chapter 19:Amino Acids: Nitrogen Disposal Chapter 20:Amino Acids: Degradation and Synthesis Chapter 21:Amino Acids: Conversion to Specialized Products Chapter 22:Nucleotide Metabolism
UNIT V: Integration of Metabolism Chapter 23:Metabolic Effects of Insulin and Glucagon Chapter 24:The Feed–Fast Cycle Chapter 25:Diabetes Mellitus Chapter 26:Obesity
UNIT VI: Medical Nutrition Chapter 27:Nutrition: Overview and Macronutrients Chapter 28:Micronutrients: Vitamins Chapter 29:Micronutrients: Minerals
UNIT VII: Storage and Expression of Genetic Information Chapter 30:DNA Structure, Replication, and Repair Chapter 31:RNA Structure, Synthesis, and Processing Chapter 32:Protein Synthesis Chapter 33:Regulation of Gene Expression Chapter 34:Biotechnology and Human Disease
Appendix Index Figure Sources
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