Casarett & Doull’s Essentials of Toxicology, Third Edition
T is updated ull-color edition o Essentials of oxicology distills the major principles and concepts o toxicology that were described in detail in the eighth edition o Casarett & Doull’s oxicology: T e Basic Science of Poisons. We are grate ul to the authors who contributed to the eighth edition o Casarett & Doull’s oxicology: T e Basic Science of Poisons; their chapters in the parent text provided the oundation or the chapters in this edition o Essentials of oxicology.
Essentials of oxicology concisely describes the expansive science o toxicology, and includes important concepts rom anatomy, physiology, and biochemistry to acilitate the understanding o the principles and mechanisms o toxicant action on speci c organ systems. We trust that this book will assist students in undergraduate and graduate courses in toxicology, as well as students rom other disciplines, to develop a strong oundation in the concepts and principles o toxicology. T e book is organized into seven units: (1) General Principles o oxicology; (2) Disposition o oxicants; (3) Nonorgandirected oxicity; (4) arget Organ oxicity; (5) oxic Agents; (6) Environmental oxicology; and (7) Applications o oxicology.
A summary o key points is included at the beginning o each chapter, and a set o review questions is provided at the end o each chapter. We invite readers to send us suggestions o ways to improve this text and we appreciate the thought ul recommendations that we received on the last edition.
We would like to acknowledge all individuals who were involved in this project. We particularly give a heart elt and sincere thanks to our amilies or their love, patience, and support during the preparation o this book. We especially appreciate Richard J. Batka and Alyssa Shapiro who provided invaluable assistance on this project. T e capable advice, guidance, and assistance o the McGraw-Hill sta is grate ully acknowledged.
Finally, we thank our students or their enthusiasm or learning and what they have taught us during their time with us.
Curtis D. Klaassen
John B. Watkins III
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